Environmental Fate Assessment
- Available data suggest that 6:2 FTOH readily degrades to form shorter-chain compounds in soil and sediment. Therefore, 6:2 FTOH is unlikely to be persistent in the environment. 6:2 FTOH has been shown to form persistent degradation products in low yields.
- Several studies have been conducted to determine whether 6:2 FTOH bioaccumulates or becomes concentrated in the bodies of living organisms. These studies indicate that organisms are capable of eliminating 6:2 FTOH and it does not bioaccumulate.
- 6:2 FTOH is volatile and may be transported in the atmosphere as a gas. 6:2 FTOH has been measured in remote environments, including the Arctic. This suggests that 6:2 FTOH may be subject to long-range environmental transport in the atmosphere.
Human and Environmental Health Hazard Assessment
- The toxicity of 6:2 FTOH has been evaluated in laboratory studies, both in vitro and in vivo. These studies show no evidence of significant toxicity at levels expected to be encountered.
- These studies indicate that 6:2 FTOH is not toxic to aquatic organisms at levels expected to be encountered.
- The European Chemicals Agency (ECHA) compiles information on various substances as part of its REACH regulations. An unpublished study referenced in the REACH dossier for 6:2 FTOH indicates that this compound meets a criterion for “T” (Toxic) in ECHA’s PBT classification scheme (STOT RE 2, H373).
International criteria define chemicals of concern as persistent organic pollutants (POPs). A POP is a substance that is resistant to environmental degradation, tends to bioaccumulate in living organisms, and has potentially significant adverse impacts on human health and the environment. Although 6:2 FTOH may be transported long distances in the environment and it meets an ECHA criterion for “T”, based on its environmental fate and toxicity (information current as of December 2016), it does not meet other criteria for a POP.
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